In order to address the differences in technical requirements of the four standards of seamless steel pipe used in natural gas gathering and transmission pipeline engineering ( including gas transmission pipeline engineering and gas gathering pipeline engineering ), theoretical analysis of the hazardous element P.S content in the chemical composition of seamless steel pipe, manufacturing method, impact test, non-metallic inclusions, band structure, etc. , has been carried out to determine their influence on the performance and quality of seamless steel pipe. Furthermore, the current situation that there is a big technical difference between the design specifications of natural gas pipeline engineering and industrial pipeline design specifications on the use of “Seamless Steel Pipe for the Transmission of Fluids GB/T 8163” has been analyzed in many aspects, including GB/T 8163 compilation historical revisions, the differences with the standard EN10216—1:2004, relevant provisions in GB150. 2—2011, etc. ; to arrive at recommendations on the application conditions of seamless steel pipe in GB/T 8163—2018. Finally, comparative analysis of the technical differences between GB6479—2013, GB/T 5310—2017, GB/T 8163—2018 and GB/T 9711—2017 is conducted, resulting in a proposal on the application .condition,togetherwith additional technical requirements, of these four seamless steel pipe standards for natural gas gathering and transmission pipeline engineering.